WNK-IN-11

$253$1,485

Products Details

Product Description

– WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1.

Web ID

– HY-112094

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C21H21Cl2N5OS

References

– [1]Yamada K, et al. Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models. J Med Chem. 2017 Aug 24;60(16):7099-7107.

CAS Number

– 2123489-30-3

Molecular Weight

– 462.40

Compound Purity

– 99.44

SMILES

– O=C(C1=CC(C2=CSC(NC)=N2)=NC=C1Cl)N3CCN(CC4=CC=C(Cl)C=C4)CC3

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : 150 mg/mL (ultrasonic)

Target

– Ser/Thr Protease

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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