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WNK-IN-11
SKU
HY-112094-10 mg
Category Reference compound
Tags Metabolic Enzyme/Protease, Others, Ser/Thr Protease
$253 – $1,485
Products Details
Product Description
– WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1.
Web ID
– HY-112094
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C21H21Cl2N5OS
References
– [1]Yamada K, et al. Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models. J Med Chem. 2017 Aug 24;60(16):7099-7107.
CAS Number
– 2123489-30-3
Molecular Weight
– 462.40
Compound Purity
– 99.44
SMILES
– O=C(C1=CC(C2=CSC(NC)=N2)=NC=C1Cl)N3CCN(CC4=CC=C(Cl)C=C4)CC3
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 150 mg/mL (ultrasonic)
Target
– Ser/Thr Protease
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.