SARS-CoV-2 EG.5.1 (Omicron) Spike RBD Protein (His)
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WISP1/CCN4 Protein, Mouse, Recombinant (His)

SKU TMPK-00732-100 μg Category Brand:

Price range: 744 CAD through 2,960 CAD

Products Details

Product Description

– The interplay between glioma stem cells (GSCs) and the tumor microenvironment plays crucial roles in promoting malignant growth of glioblastoma (GBM), the most lethal brain tumor. WISP1 is preferentially expressed and secreted by GSCs. Silencing WISP1 markedly disrupts GSC maintenance, reduces tumor-supportive TAMs (M2), and potently inhibits GBM growth. WISP1 signals through Integrin α6β1-Akt to maintain GSCs by an autocrine mechanism and M2 TAMs through a paracrine manner.

Web ID

– TMPK-00732

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Tao W, et al. Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma. Nat Commun. 2020 Jun 15;11(1):3015. doi: 10.1038/s41467-020-16827-z. PMID: 32541784; PMCID: PMC7295765.

Molecular Weight

Product type

– Recombinant-Protein

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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