WH244
Add to CompareAdded to Compare

Download Files:

WH244

SKU T88099-10 mg Category Brand:

This product is currently out of stock and unavailable.

Request Pricing

Products Details

Product Description

– WH244 is a second-generation dual degrader (PROTAC) targeting BCL-2 and BCL-xL proteins. It effectively degrades these proteins with high specificity, exhibiting a DC50 of 0.6 nM for BCL-xL and 7.4 nM for BCL-2. By promoting ubiquitination and subsequent proteasomal degradation of these proteins, WH244 restores apoptotic pathways in cells. The compound shows strong antitumor activity.

Web ID

– T88099

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C83H105ClF3N13O11S4

CAS Number

– 2941088-96-4

Molecular Weight

– C83H105ClF3N13O11S4

SMILES

– C(C1=C(CC[C@](CN2CCN(C(CN3CCN(CC(N[C@H](C(=O)N4[C@H](C(N[C@@H](C)C5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4)[C@@](C)(C)C)=O)CC3)=O)CC2)(C)C1)C7=CC=C(Cl)C=C7)N8CCN(CC8)C9=CC=C(C(NS(=O)(=O)C%10=CC(S(C(F)(F)F)(=O)=O)=C(N[C@H](CCN%11[C@@]%12(C[C@](C%11)(OC%12)[H])[H])CSC%13=CC=CC=C%13)C=C%10)=O)C=C9

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Related Products

Select options
Lys-SMCC-DM1
Lys-SMCC-DM1 Price range: 462 CAD through 2,368 CAD
1 mg1 mL * 10 mM (in DMSO)5 mg

1000 in stock

Select options
FKBP12 PROTAC dTAG-13
FKBP12 PROTAC dTAG-13 Price range: 118 CAD through 261 CAD
1 mg25 mg5 mg

1000 in stock

Select options
CDK ligand for PROTAC hydrochloride
CDK ligand for PROTAC hydrochloride Price range: 498 CAD through 3,170 CAD
1 mL * 10 mM (in DMSO)10 mg5 mg

1000 in stock

Select options
Androgen receptor antagonist 1
Androgen receptor antagonist 1 Price range: 2,432 CAD through 4,000 CAD
100 mg25 mg50 mg

1000 in stock

Add to cart
N-Boc-4-hydroxy-L-proline methyl ester
N-Boc-4-hydroxy-L-proline methyl ester 46 CAD

1000 in stock

My Cart
Wishlist
Recently Viewed
Categories

Request Data Sheet / Safty Data Sheet

Please enable JavaScript in your browser to complete this form.
=

Price Request

Please enable JavaScript in your browser to complete this form.
=

Compare Products (0 Products)
document.addEventListener('elementor/popup/show', function() { if (typeof turnstile !== 'undefined') { document.querySelectorAll('.cf-turnstile').forEach(function(el) { if (!el.dataset.rendered) { turnstile.render(el); el.dataset.rendered = true; } }); } });