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WBC100
$550 – $1,600
Products Details
Product Description
– WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc molecule glue degrader. WBC100 is a c-Myc degrader and targets ubiquitin E3 ligase CHIP mediated 26S proteasome pathway. WBC100 is used for c-Myc overexpressing tumors research[1].
Web ID
– HY-145898
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H33NO7
References
– [1]Ying Xu, et al. A Selective Small-Molecule c-Myc Degrader Potently Regresses Lethal c-Myc Overexpressing Tumors. Adv Sci (Weinh). 2022 Mar;9(8):e2104344.
CAS Number
– 2095780-08-6
Molecular Weight
– 459.53
Compound Purity
– 95.0
SMILES
– C[C@@]([C@@]1([H])C2)(CCC3=C1COC3=O)[C@]4([C@@]([C@@](O5)([H])[C@@]65C(C)C)([H])O4)[C@@]7([C@@]2([H])O7)[C@@H]6OC([C@H](N)C(C)C)=O
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– c-Myc;Molecular Glues
Pathway
– Apoptosis;PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
