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WAY-200070
SKU
HY-101271-10 mg
Category Reference compound
Tags Estrogen Receptor/ERR, Neurological Disease, Vitamin D Related/Nuclear Receptor
$106 – $1,016
Products Details
Product Description
– WAY-200070 is a selective estrogen receptor β (ERRβ) agonist with an IC50 of 2.3 nM.
Web ID
– HY-101271
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C13H8BrNO3
References
– [1]Hughes ZA, et al. WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent. Neuropharmacology. 2008 Jun;54(7):1136-42.|[2]Clipperton Allen AE, et al. Agonistic behavior in males and females: effects of an estrogen receptor beta agonist in gonadectomized and gonadally intact mice. Psychoneuroendocrinology. 2010 Aug;35(7):1008-22.|[3]Clipperton AE, et al. Differential effects of estrogen receptor alpha and beta specific agonists on social learning of food preferences in female mice. Neuropsychopharmacology. 2008 Sep;33(10):2362-75.|[4]Weiser MJ, et al. Estrogen receptor-beta agonist diarylpropionitrile: biological activities of R- and S-enantiomers on behavior and hormonal response to stress. Endocrinology. 2009 Apr;150(4):1817-25.
CAS Number
– 440122-66-7
Molecular Weight
– 306.11
Compound Purity
– 99.73
SMILES
– OC1=CC(Br)=C(OC(C2=CC=C(O)C=C2)=N3)C3=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : ≥ 31 mg/mL
Target
– Estrogen Receptor/ERR
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.