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VX-984
Price range: 213 CAD through 1,872 CAD
Products Details
Product Description
– VX-984 (M9831) is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commonly seen in glioblastoma (GBM) and non-small cell lung cancer (NSC-LC) studies.
Web ID
– T11067
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H21D2N7O
References
– Atif J Khan, et al. VX-984 is a selective inhibitor of non-homologous end joining, with possible preferential activity in transformed cells. Oncotarget. 2018 May 25;9(40):25833-25841.
CAS Number
– 1476074-39-1
Molecular Weight
– C23H21D2N7O
Compound Purity
– 0.9765
SMILES
– [2H]c1nc(C)nc([2H])c1-c1cc(NC[C@@H](C)c2cccc3c(ccnc23)C(=O)NC)ncn1
Target
– Cannabinoid Receptor
Pathway
– PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair
Product type
– Isotope products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
