VU0650786
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VU0650786

SKU T13318-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 155 CAD through 1,856 CAD

Products Details

Product Description

– VU0650786 is a selective and potent CNS-penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), exhibiting antidepressant and anxiolytic activity in rodents.

Web ID

– T13318

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H15ClFN5O2

References

– Engers JL, et al. Discovery of a Selective and CNS Penetrant Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 3 with Antidepressant and Anxiolytic Activity in Rodents. J Med Chem. 2015 Sep 24;58(18):7485-500.

CAS Number

– 1809085-30-0

Molecular Weight

– C18H15ClFN5O2

Compound Purity

– 0.9896

SMILES

– C[C@@H]1CN(C(=O)c2cc(COc3ccc(Cl)cn3)nn12)c1cccnc1F

Target

– Influenza Virus

Pathway

– Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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