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VU0404251
SKU
HY-116067-Get quote
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, mGluR, Neurological Disease
Products Details
Product Description
– U0404251 is a highly potent positive allosteric modulator of mGlu for the study of psychosis[1].
Web ID
– HY-116067
Shipping
– Room temperature
Molecular Formula
– C19H23FN2O2
References
– [1]Manka JT, et al. Optimization of an ether series of mGlu5 positive allosteric modulators: molecular determinants of MPEP-site interaction crossover. Bioorg Med Chem Lett. 2012 Oct 15;22(20):6481-5.
CAS Number
– 1276013-77-4
Molecular Weight
– 330.40
SMILES
– O=C(N[C@H](C)C(C)(C)C)C1=CC=C(N=C1)OCC2=CC=CC(F)=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mGluR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.