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Products Details
Product Description
– VU0366248 is a mGlu5 negative allosteric modulator[1].
Web ID
– HY-119765
Shipping
– Room temperature
Molecular Formula
– C14H7ClF2N2O
References
– [1]Karen J Gregory, et al. Investigating Metabotropic Glutamate Receptor 5 Allosteric Modulator Cooperativity, Affinity, and Agonism: Enriching Structure-Function Studies and Structure-Activity Relationships. Mol Pharmacol. 2012 Nov;82(5):860-75.
CAS Number
– 1243310-20-4
Molecular Weight
– 292.67
SMILES
– O=C(C1=CC(F)=CC(C#N)=C1)NC2=CC=CC(Cl)=C2F
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mGluR
Isoform
– mGluR5
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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