VU0361737
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VU0361737

SKU T6726-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 46 CAD through 360 CAD

Products Details

Product Description

– VU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of the mGlu4 receptor with an EC50 of 240 nM for human receptors and 110 nM for rat receptors. It exhibits weak activity at mGlu5 and mGlu8 receptors and is inactive at mGlu1, mGlu2, mGlu3, mGlu6, and mGlu7 receptors. The compound can penetrate the CNS.

Web ID

– T6726

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C13H11ClN2O2

References

– Engers DW, et al. J Med Chem, 2009, 52(14), 4115-4118.

CAS Number

– 1161205-04-4

Molecular Weight

– C13H11ClN2O2

Compound Purity

– 0.9909

SMILES

– COc1cc(NC(=O)c2ccccn2)ccc1Cl

Pathway

– Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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