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VTP-27999 (TFA)
$129 – $1,020
Products Details
Product Description
– VTP-27999 TFA is an alkyl amine Renin inhibitor; VTP-27999 TFA is useful for Hypertension and End-Organ Diseases.
Web ID
– HY-50769
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C28H42ClF3N4O7
References
– [1]New renin inhibitor VTP-27999 alters renin immunoreactivity and does not unfold prorenin. Hypertension. 2013 May;61(5):1075-1082.|[2]Lanqi Jia? et al. Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility ACS Med. Chem. Lett., 2011, 2 (10), pp 747-751|[3]Ishchenko A, et al. Structure-based design technology contour and its application to the design of Renin inhibitors.J Chem Inf Model. 2012 Aug 27;52(8):2089-97. Epub 2012 Jul 25.
CAS Number
– 1013937-63-7
Molecular Weight
– 639.10
Compound Purity
– 97.20
SMILES
– O=C(O)C(F)(F)F.COC(NCCO[C@@H](C1=CC(Cl)=CC=C1)[C@@]2([H])CN(CCC2)C(NC[C@@H](NC)C[C@H]3CCCOC3)=O)=O
Clinical Information
– Phase 1
Research Area
– Cardiovascular Disease
Solubility
– Ethanol : 2.4 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)
Target
– Renin
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
