VPC-13566
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VPC-13566

SKU T29111-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 64 CAD through 1,579 CAD

Products Details

Product Description

– VPC-13566 is a BF3-specific small molecule, which effectively inhibited the androgen receptor transcriptional activity and displaced the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines and reduces the growth of AR-dependent prostate cancer xenograft tumors in mice.

Web ID

– T29111

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H14N2

References

– Lallous N, et al. Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation. Mol Cancer Ther. 2016 Dec;15(12):2936-2945. Epub 2016 Oct 7.

CAS Number

– 218464-59-6

Molecular Weight

– C18H14N2

Compound Purity

– 0.9937

SMILES

– CC1=C2C(C(=CN2)C3=NC4=C(C=C3)C=CC=C4)=CC=C1

Pathway

– Endocrinology/Hormones

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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