Vortioxetine

SKU T2395-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 64 CAD through 850 CAD

Products Details

Product Description

– Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment.

Web ID

– T2395

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H22N2S

Citations

– 1. Chen Y M, Fan H, Huang J, et al. Hippocampal F3/Contactin plays a role in chronic stress-induced depressive-like effects and the antidepressant actions of vortioxetine in mice. Biochemical Pharmacology. 2022: 115097 2. Wang, Yuan, et al. Hippocampal PPARα plays a role in the pharmacological mechanism of vortioxetine, a multimodal-acting antidepressant. Frontiers in Pharmacology. 12 (2021). 3. Li W Y, Shi T S, Huang J, et al.Activation of the mTORC1 signaling cascade in the hippocampus and medial prefrontal cortex is required for the antidepressant actions of vortioxetine in mice.International Journal of Neuropsychopharmacology.2023: pyad017.

References

– Bang-Andersen B, et al. J Med Chem, 2011, 54(9), 3206-3221.

CAS Number

– 508233-74-7

Molecular Weight

– C18H22N2S

Compound Purity

– 0.9934

SMILES

– S(C1=C(C=CC=C1)N2CCNCC2)C3=C(C)C=C(C)C=C3

Pathway

– Neuroscience|||GPCR/G Protein

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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