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VH032 thiol
$390 – $670
Products Details
Product Description
– VH032 thiol (VHL ligand 6) is a VHL ligand, which binds to pan-BET inhibitor JQ1 via a linker to form PROTAC[1].
Web ID
– HY-111823
Storage Temperature
– 4°C (Powder, stored under argon)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C23H30N4O4S2
References
– [1]Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.
CAS Number
– 2098836-54-3
Molecular Weight
– 490.64
Compound Purity
– 95.91
SMILES
– CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@H](C(C)(C)S)NC(C)=O)=O)=O)C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Ligands for E3 Ligase
Isoform
– von Hippel-Lindau (VHL)
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
