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VH032-PEG5-C6-Cl
$400 – $3,250
Products Details
Product Description
– VH032-PEG5-C6-Cl (HaloPROTAC 2) is a conjugate of ligands for E3 and 21-atom-length linker. The connector of linker is Halogen group. VH032-PEG5-C6-Cl incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
Web ID
– HY-112495
Storage Temperature
– -80°C, protect from light, stored under nitrogen
Shipping
– Dry Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C38H59ClN4O9S
References
– [1]Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7.
CAS Number
– 1799506-06-1
Molecular Weight
– 783.41
Compound Purity
– 99.76
SMILES
– O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(COCCOCCOCCOCCOCCCCCCCl)=O)=O)C[C@H](O)C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 270 mg/mL (ultrasonic)|Ethanol : 100 mg/mL (ultrasonic)
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– von Hippel-Lindau (VHL)
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
