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VH032-OH
$400 – $650
Products Details
Product Description
– VH032-OH is the VH032-based VHL ligand. VH032-OH can be connected to the ligand for protein by a linker to form PROTACs[1].
Web ID
– HY-136164
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H32N4O5S
References
– [1]Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017;8(1):830. Published 2017 Oct 10.
CAS Number
– 2244684-42-0
Molecular Weight
– 488.60
Compound Purity
– 99.43
SMILES
– O=C(N(C[C@@H]1O)[C@@H](C1)C(NCC(C=CC(C(SC=N2)=C2C)=C3)=C3O)=O)[C@H](C(C)(C)C)NC(C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Ligands for E3 Ligase
Isoform
– von Hippel-Lindau (VHL)
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
