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Verrucarin A
590 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– Verrucarin A (Muconomycin A) is a Type D macrocyclic mycotoxin. Verrucarin A (VA), derived from the pathogen fungus Myrothecium verrucaria, is a protein synthesis inhibitor that inhibits the growth of leukemia cell lines and activates caspases, apoptosis, and inflammatory signaling in macrophages. It effectively increases the phosphorylation of p38 MAPK and diminishes the phosphorylation of ERK/Akt. Additionally, Verrucarin A causes cell cycle deregulation through the induction of p21 and p53 [1] [2].
Web ID
– T41240
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H34O9
CAS Number
– 3148-09-2
Molecular Weight
– C27H34O9
SMILES
– CC12[C@@]3([C@@]4(O[C@]5([C@]1(COC(=O)[C@@H](O)[C@H](C)CCOC(=O)C=CC=CC(=O)O[C@@]2(C4)[H])CCC(C)=C5)[H])[H])CO3
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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