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Products Details
Product Description
– VDR agonist 2 (compound 16i) is a VDR (vitamin D receptor) agonist that can effectively inhibit TGF-β1-induced activation of hepatic stellate cells (HSC). VDR agonist 2 has significant anti-hepatic fibrosis effects both in vitro and in vivo[1].
Web ID
– HY-149899
Shipping
– Room temperature
Molecular Formula
– C20H21F3O3
References
– [1]Xing K, et al. Design, synthesis and anti-hepatic fibrosis activity of novel diphenyl vitamin D receptor agonists. Eur J Med Chem. 2023 Oct 5;258:115596.
Molecular Weight
– 366.37
SMILES
– FC(F)(CCCOC1=CC=C(/C=C/C2=CC=C(C(CO)=C2)CO)C=C1)F
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– VD/VDR
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
