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Val-Cit
SKU
HY-140014-10 mg
Category ADC Related
Tags ADC Linker, Antibody-drug Conjugate/ADC Related, Cancer
$290 – $1,750
Products Details
Product Description
– Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Web ID
– HY-140014
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C11H22N4O4
References
– [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
CAS Number
– 159858-33-0
Molecular Weight
– 274.32
Compound Purity
– 99.38
SMILES
– O=C(O)[C@H](CCCNC(N)=O)NC([C@H](C(C)C)N)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– H2O : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– ADC Linker
Isoform
– Cleavable Linker;Protease Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.