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Products Details
Product Description
– USP1-IN-4 (compound 10) is an effective USP1 inhibitor with an IC50 value of 2.44 nM. USP1-IN-4 has anticancer activity and synergistic activity with various anticancer drugs[1].
Web ID
– HY-153731
Shipping
– Room temperature
Molecular Formula
– C26H23F3N6
References
– [1]Cai S, et al. Nitrogen-containing fused heteroaromatic bicyclic compounds as USP1 inhibitors and the use thereof. China,WO 2022/253188 A.2022-8-12.
CAS Number
– 2878441-72-4
Molecular Weight
– 476.50
SMILES
– FC(F)(C1=CN(C)C(C2=CC=C(CC3=NC=C4C=NC(C5=C(C(C)C)C=CC=C5)=NN43)C=C2)=N1)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Deubiquitinase
Isoform
– USP1
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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