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Uridine diphosphate glucuronic acid (ammonium)

$383$979

Products Details

Product Description

– Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum[1].

Web ID

– HY-125954A

Shipping

– Room temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C15H22N2O18P2.xNH3

References

– [1]DUTTON GJ. Uridine diphosphate glucuronic acid as glucuronyl donor in the synthesis of ester, aliphatic and steroid glucuronides. Biochem J. 1956 Dec;64(4):693-701.|[2]Annika J E Borg, et al. Mechanistic characterization of UDP-glucuronic acid 4-epimerase. FEBS J. 2021 Feb;288(4):1163-1178.

CAS Number

– 43195-60-4

Molecular Weight

– N/A

SMILES

– O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O)=O)(O)=O)(O)=O)O2)NC1=O.N.[x]

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Endogenous Metabolite

Isoform

– Human Endogenous Metabolite

Pathway

– Metabolic Enzyme/Protease

Product type

– Biochemical Assay Reagents

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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