UR-PI376
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UR-PI376

SKU T35003-25 mg Category Brand:

Price range: 2,432 CAD through 4,000 CAD

Products Details

Product Description

– UR-PI376 is a histamine H4 receptor agonist (hH4R agonist) (pEC50 = 7.47, alpha = 0.93), with low activity for hH1R and hH2R and significant selectivity for hH3R (pKB = 6.00, alpha =- 0.28), as in stable-use a membrane preparation of hH(x)R-expressing Sf9 cells for state GTPase detection.

Web ID

– T35003

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H22N6S

References

– Geyer R, Nordemann U, Strasser A, Wittmann HJ, Buschauer A. Conformational Restriction and Enantioseparation Increase Potency and Selectivity of Cyanoguanidine-Type Histamine H(4) Receptor Agonists. J Med Chem. 2016 Apr 5. [Epub ahead of print] PubMed PMID: 27007611.

CAS Number

– 1192559-94-6

Molecular Weight

– C17H22N6S

SMILES

– C(CCCN=C(NCCSC1=CC=CC=C1)NC#N)C2=CN=CN2

Target

– Others

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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