UPGL00004
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UPGL00004

SKU T17206-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 69 CAD through 632 CAD

Products Details

Product Description

– UPGL00004 is a potent glutaminase C (GAC) inhibitor with an IC50 of 29 nM. Kd of UPGL00004 for GAC was 27 nM. UPGL00004 has a strong inhibitory effect on the proliferation of highly aggressive triple negative breast cancer cell lines.

Web ID

– T17206

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H26N8O2S2

References

– Huang Q, et al. Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism. J Biol Chem. 2018 Mar 9;293(10):3535-3545.

CAS Number

– 1890169-95-5

Molecular Weight

– C25H26N8O2S2

Compound Purity

– 0.9744

SMILES

– O=C(Cc1ccccc1)Nc1nnc(NC2CCN(CC2)c2nnc(NC(=O)Cc3ccccc3)s2)s1

Target

– Others

Pathway

– Proteases/Proteasome

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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