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Upacicalcet
Products Details
Product Description
– Upacicalcet is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT)[1].
Web ID
– HY-109106
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C11H14ClN3O6S
References
– [1]Hoy SM. Upacicalcet: First Approval. Drugs. 2021;81(13):1593-1596.
CAS Number
– 1333218-50-0
Molecular Weight
– 351.76
SMILES
– O=C(NC[C@H](N)C(O)=O)NC1=CC(S(=O)(O)=O)=CC(Cl)=C1C
Clinical Information
– Launched
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– CaSR
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.