UNC6852

SKU T13954-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 216 CAD through 2,368 CAD

Products Details

Product Description

– UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC.

Web ID

– T13954

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C43H48N10O6S

References

– Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27(1):47-56.e15.

CAS Number

– 2688842-08-0

Molecular Weight

– C43H48N10O6S

Compound Purity

– ≥98%

SMILES

– Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCNC(=O)c2ccc(cc2)-c2cnc(NCc3ccco3)n3cnnc23)C(C)(C)C)cc1

Target

– Others

Pathway

– Chromatin/Epigenetic|||PROTAC

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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