UNC2025

SKU T7007-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 33  USD through 369  USD

Products Details

Product Description

– UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.

Web ID

– T7007

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H40N6O

Citations

– 1. Wei S, Guan G, Luan X, et al.NLRP3 inflammasome constrains liver regeneration through impairing MerTK-mediated macrophage efferocytosis.Science Advances.2025, 11(1): eadq5786.

References

– Zhang W, et al. J Med Chem. 2014, 57(16), 7031-7041.

CAS Number

– 1429881-91-3

Molecular Weight

– C28H40N6O

Compound Purity

– 0.9953

SMILES

– CCCCNc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(CN2CCN(C)CC2)cc1

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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