ULK1-IN-2
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ULK1-IN-2

SKU T63343-1 mg Category Brand:

Price range: 82 CAD through 3,568 CAD

Products Details

Product Description

– ULK1-IN-2 is a potent ULK1 inhibitor with potential anticancer activity, inducing apoptosis while blocking autophagy.ULK1-IN-2 has high cytotoxicity against cancer cells, with an IC50 value of 1.94 μM against A549 cells.ULK1-IN-2 can be used for the study of non-small-cell lung cancer.

Web ID

– T63343

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H16BrFN4O6

References

– Sun D, Yang Z, Zhen Y, et al. Discovery of 5-bromo-4-phenoxy-N-phenylpyrimidin-2-amine derivatives as novel ULK1 inhibitors that block autophagy and induce apoptosis in non-small cell lung cancer. Eur J Med Chem. 2020;208:112782.

CAS Number

– 2497409-01-3

Molecular Weight

– C19H16BrFN4O6

Compound Purity

– 0.9976

SMILES

– O(C)C1=C(OC)C=C(NC=2N=C(OC3=C(F)C=C(N(=O)=O)C=C3)C(Br)=CN2)C=C1OC

Pathway

– Autophagy|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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