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UF010
$35 – $330
Products Details
Product Description
– UF010 is a selective inhibitor of class I HDAC. UF010 has cytotoxicity to cancer cells and reduces neuroinflammation in the hippocampus. UF010 can be used for the research of neurological diseases[1][2][3].
Web ID
– HY-18976
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C11H15BrN2O
References
– [1]Mattar P, et al. A Casz1–NuRD complex regulates temporal identity transitions in neural progenitors [J]. Scientific reports, 2021, 11(1): 3858.|[2]Pulya S, et al. Selective inhibition of histone deacetylase 3 by novel hydrazide based small molecules as therapeutic intervention for the treatment of cancer [J]. European Journal of Medicinal Chemistry, 2022, 238: 114470.|[3]Dai Y, et al. Classical HDACs in the regulation of neuroinflammation[J]. Neurochemistry International, 2021, 150: 105182.
CAS Number
– 537672-41-6
Molecular Weight
– 271.15
Compound Purity
– 99.84
SMILES
– O=C(NNCCCC)C1=CC=C(Br)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology; Neurological Disease
Solubility
– DMSO : ≥ 100 mg/mL
Target
– HDAC;JAK;MyD88;NF-κB;Toll-like Receptor (TLR)
Pathway
– Cell Cycle/DNA Damage;Epigenetics;Immunology/Inflammation;JAK/STAT Signaling;NF-κB;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
