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UCT943
SKU
HY-112435-10 mg
Category Reference compound
Tags Anti-infection;PI3K/Akt/mTOR, Infection, Parasite;PI4K
$550 – $2,950
Products Details
Product Description
– UCT943 is a next-generation Plasmodium falciparum PI4K inhibitor. UCT943 inhibits the P. vivax PI4K (PvPI4K) enzyme with an IC50 of 23 nM[1].
Web ID
– HY-112435
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H20F3N5O
References
– [1]Brunschwig C, et al. UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria. Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00012-18.
CAS Number
– 1450666-80-4
Molecular Weight
– 427.42
Compound Purity
– 98.70
SMILES
– FC(F)(F)C1=CC=C(C2=NC(C3=CC=C(C(N4CCNCC4)=O)C=C3)=CN=C2N)C=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Parasite;PI4K
Isoform
– PI4K;Plasmodium
Pathway
– Anti-infection;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.