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Products Details
Product Description
– UCM-1336 is a potent ICMT inhibitor, with an IC50 of 2 μM. UCM-1336 induces mislocalization of endogenous Ras, decreases Ras activation and induces cell death by autophagy and apoptosis[1].
Web ID
– HY-155954
Shipping
– Room temperature
Molecular Formula
– C26H37N3O2
References
– [1]Nagore Marín-RamosA, Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia. J Med Chem. 2019 Jul 11;62(13):6035-6046.
CAS Number
– 1621535-90-7
Molecular Weight
– 423.59
SMILES
– O=C(CCN(CCCCCCCC)CCC(NC1=CC=CC=C1)=O)NC2=CC=CC=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Autophagy
Pathway
– Apoptosis;Autophagy
Product type
– Reference compound
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