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Ubiquitination-IN-1
$80 – $580
Products Details
Product Description
– Ubiquitination-IN-1 (compound 24) is a ubiquitination and Cksl-Skp2 protein-protein interaction (IC50=0.17 μM) inhibitor. Ubiquitination-IN-1 increases levels of p27. Ubiquitination-IN-1 has the potential for treatment disease by blocking the degradation of tumor suppressors[1].
Web ID
– HY-135199
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H14F3N3O2S
References
– [1]David Carroll, et al.Quinoline derivatives useful as ubiquitination inhibitors. WO2016025779A1.
CAS Number
– 1819330-15-8
Molecular Weight
– 429.41
Compound Purity
– 98.22
SMILES
– O=S(C1=CC=CC(C(F)(F)F)=C1)(NC2=C3N=CC=CC3=C(C4=CC=CN=C4)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 83.33 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– E1/E2/E3 Enzyme
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
