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Tyrosinase-IN-16

SKU HY-125762-Get quote Category Tags , ,

Products Details

Product Description

– Tyrosinase-IN-16 (compound 19a) is a tyrosine kinase (Tyrosinase) inhibitor with Ki=470 nM. Tyrosinase-IN-16 is cytotoxic to B16F10 cells, with >90% inhibition at 20 μM[1].

Web ID

– HY-125762

Shipping

– Room temperature

Molecular Formula

– C8H6BrN3S

References

– [1]Choi J, et al. Ensemble-Based Virtual Screening Led to the Discovery of New Classes of Potent Tyrosinase Inhibitors. J Chem Inf Model. 2016 Feb 22;56(2):354-67.

CAS Number

– 126651-85-2

Molecular Weight

– 256.12

SMILES

– S=C1NNC(C2=CC=CC(Br)=C2)=N1

Clinical Information

– No Development Reported

Research Area

– cancer

Solubility

– 10 mM in DMSO

Target

– Tyrosinase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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