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Products Details
Product Description
– Tubulin polymerization-IN-57 (compound 5a) is a tubulin inhibitor and is an α-naphthoxy-substituted carbendazim (HY-13582) derivative. Tubulin polymerization-IN-57 induces mitotic arrest and inhibits cancer cell proliferation[1].
Web ID
– HY-155459
Shipping
– Room temperature
Molecular Formula
– C19H15N3O3
References
– [1]Cano-González L et al. Structure-Based Optimization of Carbendazim-Derived Tubulin Polymerization Inhibitors through Alchemical Free Energy Calculations. J Chem Inf Model. 2023 Nov 27;63(22):7228-7238.
CAS Number
– 95385-38-9
Molecular Weight
– 333.34
SMILES
– O=C(OC)NC1=NC2=CC(OC3=C4C=CC=CC4=CC=C3)=CC=C2N1
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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