Tubulin polymerization-IN-43
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Tubulin polymerization-IN-43

SKU T77647-1 mg Category Brand:

Price range: 152 CAD through 1,904 CAD

Products Details

Product Description

– Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.Tubulin polymerization-IN-43 has multiple effects, disrupting the cellular microtubule network by targeting the colchicine locus and promoting cell cycle arrest and apoptosis in leukaemia cells. Tubulin polymerisation-IN-43 has multiple effects, promoting leukaemia cell cycle arrest in G2/M phase and apoptosis by targeting Colchicine sites to disrupt the cellular microtubule network.

Web ID

– T77647

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H13F4N3O

References

– Wu H, et al. Discovery of novel N-aryl-2-trifluoromethyl-quinazoline-4-amine derivatives as the inhibitors of tubulin polymerization in leukemia cells. Eur J Med Chem. 2023 Aug 5;256:115470.

CAS Number

– 2773345-90-5

Molecular Weight

– C17H13F4N3O

Compound Purity

– 0.9985

SMILES

– N(C)(C=1C2=C(N=C(C(F)(F)F)N1)C=CC(F)=C2)C3=CC=C(OC)C=C3

Pathway

– Apoptosis|||Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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