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Products Details
Product Description
– Tubulin inhibitor 25 is a potent tubulin inhibitor with an IC50 value of 0.98 μM. Tubulin inhibitor 25 exhibits remarkable activity against cancer cell line HT29. Tubulin inhibitor 25 displays the potent inhibition on cell migration and tube formation that contributes to the anti-angiogenesis[1].
Web ID
– HY-146778
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H22O8
References
– [1]Shao YY, et al. Synthesis and biological evaluation of novel shikonin-benzo[b]furan derivatives as tubulin polymerization inhibitors targeting the colchicine binding site. Eur J Med Chem. 2020;190:112105.
CAS Number
– 2411697-71-5
Molecular Weight
– 462.45
SMILES
– O=C(C1=CC2=CC=CC(OC)=C2O1)O[C@@H](C(C3=O)=CC(C4=C3C(O)=CC=C4O)=O)C/C=C(C)/C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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