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Products Details
Product Description
– TT-OAD2 free base is a non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist with an EC50 of 5 nM. TT-OAD2 free base has the potential for diabetes treatment[1][2].
Web ID
– HY-129658
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C50H47Cl2N3O6
References
– [1]Transtech Pharma, et al. Substituted azoanthracene derivatives, pharmaceutical compositions, and methods of use thereof. WO2010114824A1.|[2]Zhao P, et al. Activation of the GLP-1 receptor by a non-peptidic agonist. Nature. 2020 Jan;577(7790):432-436.
CAS Number
– 1246826-07-2
Molecular Weight
– 856.83
SMILES
– O=C(O)[C@H](CC1=CC=C(C2=C(C)C(C)=NC=C2)C=C1)NC([C@H]3N([C@H](C4=CC=CC=C4)CC)CC5=C(C=C(OC[C@H](C6=CC=C(OCC7=CC=C(Cl)C(Cl)=C7)C=C6)O8)C8=C5)C3)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– GCGR
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
