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TRPC6-IN-3
SKU
HY-148129-1 mg
Category Reference compound
Tags Cardiovascular Disease, Membrane Transporter/Ion Channel;Neuronal Signaling, TRP Channel
$220 – $4,800
Products Details
Product Description
– TRPC6-IN-3 (compound 17) is a potent, orally active transient receptor potential C6 ion channel (TRPC6) inhibitor. TRPC6-IN-3 modulates not only intracellular calcium concentration, but also membrane potential by modulating the flux of cations including calcium and sodium ions. TRPC6-IN-3 can be used in research of respiratory system[1].
Web ID
– HY-148129
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C22H22FN5O3
References
– [1]Thierry B, et, al. Inhibitors of TRPC6 for treating respiratory conditions. WO2021209510.
CAS Number
– 2311863-36-0
Molecular Weight
– 423.44
Compound Purity
– 99.62
SMILES
– O=C(N1CCC(C2=NN=C(N)C=C2)CC1)C3=NC=C(OC4=CC=C(F)C=C4)C(OC)=C3
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– TRP Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.