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Products Details
Product Description
– TrkB-IN-1 is a potent and orally active TrkB agonist and has favorable PK properties. TrkB-IN-1 reverses the cognitive defects in an AD mouse model and can be used for alzheimer’s disease research[1].
Web ID
– HY-153189
Shipping
– Room temperature
Molecular Formula
– C19H16N2O6
References
– [1]Chun Chen, et al. The prodrug of 7,8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer’s disease. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):578-583.
CAS Number
– 1609067-49-3
Molecular Weight
– 368.34
SMILES
– O=C1C=C(C2=CC=CC=C2)OC3=C(OC(NC)=O)C(OC(NC)=O)=CC=C13
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Trk Receptor
Isoform
– TrkB
Pathway
– Neuronal Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
