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Products Details
Product Description
– Trimethoprim N-oxide (Trimethoprim 1-N-oxide) belongs to human urinary metabolites. Trimethoprim N-oxide is generated by oxidation of nitrogen atoms in the pyrimidine ring. Trimethoprim N-oxide is formed predominantly by CYP1A2 in human liver microsomes[1].
Web ID
– HY-100644
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H18N4O4
References
– [1]Goldman JL, et al. In Vitro Hepatic Oxidative Biotransformation of Trimethoprim. Drug Metab Dispos. 2015 Sep;43(9):1372-80.
CAS Number
– 27653-68-5
Molecular Weight
– 306.32
SMILES
– NC1=NC(N)=C(CC2=CC(OC)=C(OC)C(OC)=C2)C=[N+]1[O-]
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
