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Products Details
Product Description
– Triciribine phosphate (TCN-P) inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate also inhibits IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity[1].
Web ID
– HY-10250
Shipping
– Room temperature
Molecular Formula
– C13H17N6O7P
References
– [1]E C Moore, Inhibition of two enzymes in de novo purine nucleotide synthesis by triciribine phosphate (TCN-P). Biochem Pharmacol. 1989, 38, 22.
CAS Number
– 61966-08-3
Molecular Weight
– 400.28
SMILES
– NC1=NN(C)C2=C3C1=CN([C@@H]4O[C@@H]([C@H]([C@H]4O)O)COP(O)(O)=O)C3=NC=N2
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– ATP Synthase
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
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