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Products Details
Product Description
– TPE-1p is a cascade-activated AIEgen-peptide probe. TPE-1p self-assembles in aqueous solution to exhibit bright fluorescence in response to alkaline phosphatase (ALP) and ChT-L. TPE-1p can be utilized to noninvasively assess the inhibition efficiency of a ChT-L inhibitor in cells[1].
Web ID
– HY-149865
Shipping
– Room temperature
Molecular Formula
– C53H49N4O15P
References
– [1]Jiao Q, et al. Cascade-Activated AIEgen-Peptide Probe for Noninvasively Monitoring Chymotrypsin-like Activity of Proteasomes in Cancer Cells. Anal Chem. 2023 Jun 13;95(23):9097-9106.
Molecular Weight
– 1012.95
SMILES
– O=C(NC(C(NC(CC1=CC=C(O)C=C1)C(NC(C(NC(CC(O)=O)C(O)=O)=O)CC(O)=O)=O)=O)CC2=CC=C(OP(O)(O)=O)C=C2)C3=CC=C(/C(C4=CC=CC=C4)=C(C5=CC=CC=C5)/C6=CC=CC=C6)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Fluorescent Dye;Phosphatase
Pathway
– Metabolic Enzyme/Protease;Others
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
