TP0427736
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TP0427736

SKU T24897-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 155 CAD through 1,512 CAD

Products Details

Product Description

– TP0427736 is a potent and selective inhibitor of ALK5 with an IC50 of 2.72 nM, 300-fold higher than the inhibitory effect on ALK3. TP0427736 reduces TGF-β-induced growth inhibition in human outer root sheath cells and elongates the anagen phase in mouse hair follicles.

Web ID

– T24897

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H10N4S2

References

– Naruse T, et al. Novel ALK5 inhibitor TP0427736 reduces TGF-β　induced growth inhibition in human outer root sheath cells and elongates anagen phase in mouse hair follicles. Pharmacol Rep. 2017 Jun;69(3):485-491.

CAS Number

– 864374-00-5

Molecular Weight

– C14H10N4S2

Compound Purity

– 0.9767

SMILES

– CC=1N=C(C2=C(NC=N2)C=3C=C4C(=CC3)N=CS4)SC1

Pathway

– Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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