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TP003
$150 – $800
Products Details
Product Description
– TP003 is a non-selective benzodiazepine site agonist with EC50s of 20.3, 10.6, 3.24, 5.64 nM for α1β2γ2, α2β3γ2, α3β3γ2, α5β2γ2, respectively. TP003 induces anxiolysis via α2GABAA receptors[1].
Web ID
– HY-103512
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C23H16F3N3O
References
– [1]Elena Neumann, et al. TP003 is a non-selective benzodiazepine site agonist that induces anxiolysis via α2GABA<sub>A</sub> receptors. Neuropharmacology. 2018 Dec;143:71-78.
CAS Number
– 628690-75-5
Molecular Weight
– 407.39
Compound Purity
– 98.99
SMILES
– N#CC1=CC(F)=CC=C1C2=CC(C3=CN=C4C(F)=C(C(C)(O)C)C=CN43)=CC=C2F
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– GABA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
