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Tomaymycin DM
$850 – $4,800
Products Details
Product Description
– Tomaymycin DM, a DNA alkylator, is a derivative of Tomaymycin, it is a PBD dimer, which is attached to tumor targeting antibodies to create antibody-drug conjugates (ADCs).
Web ID
– HY-102001
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H14N2O3
References
– [1]Dr. Julia Mantaj, et al. From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody–Drug Conjugates (ADCs). Angew Chem Int Ed Engl. 2017 Jan 9; 56(2): 462–488.
CAS Number
– 945490-09-5
Molecular Weight
– 258.27
Compound Purity
– 98.01
SMILES
– O=C1N2[C@](CC(C2)=C)([H])C=NC3=CC(O)=C(OC)C=C13
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– ADC Cytotoxin
Isoform
– Pyrrolobenzodiazepines
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
