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Products Details
Product Description
– TNF-α-IN-8 (compound I-42) is a TNF-α inhibitor. TNF-α-IN-8 is an isoindole-imide compound. TNF-α-IN-8 can be used for the research of cancer, heart disease, osteoporosis, inflammatory, allergic and autoimmune diseases[1]. TNF-α-IN-8 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Web ID
– HY-148908
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C15H12N6O5
References
– [1]Robarge MJ, et al. ISOINDOLE-IMIDE COMPOUNDS, COMPOSITIONS, AND USES THEREOF. WO/2002/059106. 2002.
CAS Number
– 444287-85-8
Molecular Weight
– 356.29
SMILES
– [N-]=[N+]=NCC(NC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Biochemical Assay Reagents
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
