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Product Description
– Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms[1].
Web ID
– HY-D0984
Shipping
– Room temperature
Molecular Formula
– C25H25N2O3
Citations
– Adv Sci (Weinh). 2023 Jan 15;e2203869.|Aquaculture. 5 October 2022, 738900.|Autophagy. 2021 Nov;17(11):3592-3606.|Biochem Biophys Res Commun. 9 July 2022.|Cell Signal. 2023 Nov 13:110969.|Endocrinology. 2020 Sep 1;161(9):bqaa119.|Int J Mol Sci. 2023 Jul 17, 24(14), 11554.|J Thromb Haemost. 2021 Aug 19.|Toxicon. 2 July 2022.|Adv Mater. 2023 Mar 29;e2211609.|Cell Signal. 2020 Nov;75:109733.|Exp Eye Res. 2021 May 28;108640.
References
– [1]Chowdhury SR, et al. Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria. Biosci Rep. 2015 Dec 8;36(1):e00286.|[2]Monteith A, et al. Imaging of mitochondrial and non-mitochondrial responses in cultured rat hippocampal neurons exposed to micromolar concentrations of TMRM. PLoS One. 2013;8(3):e58059.|[3]Crowley LC, et al. Measuring Mitochondrial Transmembrane Potential by TMRE Staining. Cold Spring Harb Protoc. 2016 Dec 1;2016(12):pdb.prot087361.
CAS Number
– 115532-49-5
Molecular Weight
– 401.48
SMILES
– O=C(C1=CC=CC=C1C2=C3C=CC(N(C)C)=CC3=[O+]C4=C2C=CC(N(C)C)=C4)OC
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Fluorescent Dye
Pathway
– Others
Product type
– Dye Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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