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TMPPAA
SKU
HY-119806-Get quote
Category Reference compound
Tags 5-HT Receptor, GPCR/G Protein;Neuronal Signaling, Neurological Disease
Products Details
Product Description
– TMPPAA is an allosteric agonist and positive allosteric modulator of the 5-HT3 receptor. TMPPAA enhances 5-HT-mediated 5-HT3AR signaling[1].
Web ID
– HY-119806
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C15H21NO2
References
– [1]Gasiorek A, et al. Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 receptors. Biochem Pharmacol. 2016 Jun 15;110-111:92-108.
CAS Number
– 844900-50-1
Molecular Weight
– 247.33
SMILES
– O=C(/C=C/C1=CC=C(C=C1)OC)NC(CC)CC
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.