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Products Details
Product Description
– TLR8 agonist 4 showed effective inhibition on wild-type and drug-resistant (lamivudine and entecavir) HBV strains. The IC50 values are 0.15 and 0.10 respectively μM.
Web ID
– HY-144215
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C28H27N5O5S
References
– [1]Qiu J, et al. Design and synthesis of novel quinazolinone derivatives as anti-HBV agents with TLR8 agonist effect. Eur J Med Chem. 2022 Mar 5;231:114159.
CAS Number
– 2761697-69-0
Molecular Weight
– 545.61
SMILES
– COC1=C(C=CC=C1)CSC2=NC3=CC=C(C=C3C(N2CC4=CC=CO4)=O)OCCCOC5=NC(N)=NC=C5
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– HBV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
