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Products Details
Product Description
– TLR8 agonist 2 is a potent and selective TLR8 agonist with an EC50 of 3 nM for human TLR8. TLR8 agonist 2 shows less active against human TLR7 (EC50 of 33.33 μM)[1].
Web ID
– HY-141454
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H22N8
References
– [1]Zhe Cai, et al. Tlr8 agonist. WO2020057604A1.
CAS Number
– 2412937-64-3
Molecular Weight
– 326.40
SMILES
– CCCC[C@@](CC1=NN=CN1)(C)NC2=NC(N)=NC3=C2C=CN=C3
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Toll-like Receptor (TLR)
Isoform
– TLR7;TLR8
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
