TL4-12

SKU T26280-1 mg Category Brand:

Price range: 147 CAD through 2,208 CAD

Products Details

Product Description

– TL4-12 is a specific MAP4K2/GCK inhibitor that inhibits IKZF1 and BCL-6.TL4-12 inhibits MM cell proliferation and induces apoptosis, and can be used in the study of multiple myeloma (MM).

Web ID

– T26280

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H27F3N6O2

References

– Shirong Li, et al. Targeting the GCK pathway: a novel and selective therapeutic strategy against RAS-mutated multiple myeloma. Blood. 2021 Apr 1;137(13):1754-1764.

CAS Number

– 1620820-12-3

Molecular Weight

– C25H27F3N6O2

Compound Purity

– 0.9838

SMILES

– O=C(NC=1C=C(C=C(C1)C(F)(F)F)N2CCN(C)CC2)C3=CC=C(C(OC4=NC=NC(=C4)NC)=C3)C

Pathway

– Immunology/Inflammation|||Apoptosis

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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